Increasing to 4 layers of denim would almost always cause a failure to expand. Have carried as law enforcement.
I knew there was a hospital less than half a mile away and may have had a good chance of surviving. The Hornady Custom XTP achieved approximately 13 inches of penetration but less expansion than the other cartridges Ammunition penetration comparison.
Ergo accuracy as a metric will not be used.
Always carry at least one spare magazine and two is better.
Handgun Cartridge Power Chart - Condensed Version
Handgun Calibers Comparison: From Smallest to Largest